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Adiponectin: Implications in Health and Diseases
Seema Gupta
(Author)
·
V. N. Satyawali
(Author)
·
Sanjeev Kumar Shukla
(Author)
·
Scholars' Press
· Paperback
Adiponectin: Implications in Health and Diseases - Gupta, Seema ; Satyawali, V. N. ; Shukla, Sanjeev Kumar
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Synopsis "Adiponectin: Implications in Health and Diseases"
Adiponectin is the name originated from its distinctive molecular characteristics ("adipo" ] "nectin" = "adiponectin") as it is a product of novel gene apM1 which is specific to adipocytes and uniquely possess a collagen-like domain with a nectin-like adherent property. Adiponectin is the most abundant peptide secreted by adipocytes, whose altered levels play a central role in obesity-related diseases, including insulin resistance/type 2 diabetes and cardiovascular disease. It is known to exert anti-diabetic and anti-atherosclerotic effects via adiponectin receptors (Adipors); AdipoR1 and AdipoR2. Adiponectin has direct actions in liver, skeletal muscle and the vasculature. Adiponectin administration in humans and rodents has insulin-sensitizing, anti-atherogenic, and anti-inflammatory effects and in certain settings, also decreases body weight. Therefore, adiponectin replacement therapy in humans may suggest potential versatile therapeutic targets in the treatment of obesity, insulin resistance/type 2 diabetes, cardiovascular disease and atherosclerosis.
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All books in our catalog are Original.
The book is written in English.
The binding of this edition is Paperback.
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