Synopsis "Drug Target Selection and Validation"
Table of Contents DRUG DISCOVERY AND DESIGN SERIES Volume 1: Drug Target selection and validation. 1. Drug discovery paradigms: target-based drug discovery Chonny Herrera-Acevedo, Camilo Perdomo-Madrigal, José Alixandre de Sousa Luis, Luciana Scotti, Marcus Tullius Scotti 2. Drug discovery paradigms: phenotypic-based drug discovery Alan Talevi, Carolina L. Bellera 3. Target Identification Approaches in Drug Discovery Azhar Rasul, Ammara Riaz, Iqra Sarfraz, Samreen Gul Khan, Ghulam Hussain, Rabia Zara, Ayesha Sadiqa, Gul Bushra, Saba Riaz, Muhammad Javid Iqbal, Mudassir Hassan, Khatereh Khorsandi 4. Introduction to target validation Cecilia Ortíz, Santiago Ruatta, Marcelo Comini 5. Structure-based binding pocket detection and druggability assessment Santiago Rodriguez, Juan I. Alice, Carolina L. Bellera, Alan Talevi 6. Network-Based Target Identification Zengrui Wu, Yun Tang 7. The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We? Attila Seyhan 8. Metabolic Control Analysis for drug target selection against human diseases Javier Belmont-Díaz, Citlali Vázquez, Rusely Encalada, Rafael Moreno-Sánchez, Paul A. M. Michels, Emma Saavedra 9. Progress on open chemoinformatic tools for drug discovery José L. Medina-Franco, Rodrigo Gutiérrez-Nieto, Homero Gómez-Velasco
