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portada G Protein-Coupled Receptors in Drug Discovery
Type
Physical Book
Publisher
Language
English
Pages
376
Format
Paperback
ISBN13
9780367392512
Edition No.
1

G Protein-Coupled Receptors in Drug Discovery

Kenneth H. Lundstrom (Editor), Mark L. Chiu (Editor) (Author) · Crc Press · Paperback

G Protein-Coupled Receptors in Drug Discovery - Kenneth H. Lundstrom (Editor), Mark L. Chiu (Editor)

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Synopsis "G Protein-Coupled Receptors in Drug Discovery"

The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled Receptors in Drug Discovery describes the physiological roles of GPCRs and their involvement in various human diseases.The book presents current approaches in drug discovery that include target selection, establishment of screening and functional assays. It also covers recombinant GPCR expression for drug screening and structural biology, different methods for structural characterization of GPCRs, and the importance of bioinformatics. The book has been carefully edited to avoid overlapping information, some duplication has been intentionally permitted so that each chapter can function as an independent unit. Providing in-depth discussions on structure and dynamics of GPCRs, this book outlines the importance of the GPCRs to drug discovery in general and drug targets specifically.Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

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