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portada Impact of Neo-Adjuvant Chemotherapy in Colon Cancer
Type
Physical Book
Language
Inglés
Pages
92
Format
Paperback
Dimensions
22.9 x 15.2 x 0.6 cm
Weight
0.15 kg.
ISBN13
9786205868645

Impact of Neo-Adjuvant Chemotherapy in Colon Cancer

Nabila Talbi (Author) · Mourad Abid (Author) · Our Knowledge Publishing · Paperback

Impact of Neo-Adjuvant Chemotherapy in Colon Cancer - Talbi, Nabila ; Abid, Mourad

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Origin: U.S.A. (Import costs included in the price)
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Synopsis "Impact of Neo-Adjuvant Chemotherapy in Colon Cancer"

Surgery with adjuvant chemotherapy is currently the gold standard in the management of locally advanced non-metastatic colon cancer. However, a peri-operative strategy is beginning to emerge. The aim of this randomized trial is to report a series of 110 patients operated on for locally advanced non-metastatic colon cancer with evaluation of the impact of neo-adjuvant chemotherapy versus primary surgery in terms of overall survival and recurrence-free survival, with the quality of the complete surgery and histological tumor regression as well as postoperative morbidity and mortality as endpoints. The results show a benefit of neoadjuvant chemotherapy on the quality of surgical excision by down sizing as well as a reduction of major postoperative morbidity and on the anatomopathological results by down staging and partial histological response. There seems to be a superiority of neoadjuvant chemotherapy in terms of median overall survival and recurrence-free survival. This new peri-operative strategy seems to provide tumor control. It would be a kind of pre-enabling for surgery.

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