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Multicomponent synthesis of 4H-pyran-3-carboxylate derivatives
Dhaval B. Patel
(Author)
·
LAP Lambert Academic Publishing
· Paperback
Multicomponent synthesis of 4H-pyran-3-carboxylate derivatives - Patel, Dhaval B.
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Synopsis "Multicomponent synthesis of 4H-pyran-3-carboxylate derivatives"
A simple, versatile, one-pot, multi-component reaction (MCR) of ethyl 6-amino-5-cyano-2-methyl-4H-pyran-3-carboxylate derivatives has been achieved in the presence of urea as a potent catalyst in water-ethanol as a green solvent system. Reaction was proceeding via three component reaction by utilizing various aldehyde, malononitrile and ethylacetoacetate at room temperature. All Synthesized products were confirmed by Mass, 1H-NMR, IR and Melting point. Mild reaction conditions, excellent yields, easy isolation of products, no column chromatographic separation, reusability of reaction media.
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The book is written in English.
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