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portada oncogenes: an introduction to the concept of cancer genes
Type
Physical Book
Publisher
Year
1988
Language
Inglés
Pages
300
Format
Paperback
Dimensions
23.5 x 15.9 x 1.8 cm
Weight
0.55 kg.
ISBN
0387964231
ISBN13
9780387964232

oncogenes: an introduction to the concept of cancer genes

Kathy B. Burck (Author) · Edison T. Liu (Author) · Joshua Lederberg (Preface by) · Springer · Paperback

oncogenes: an introduction to the concept of cancer genes - Burck, Kathy B. ; Lederberg, Joshua ; Liu, Edison T.

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£ 116.78

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Origin: U.S.A. (Import costs included in the price)
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Synopsis "oncogenes: an introduction to the concept of cancer genes"

"Cancer viruses" have played a paradoxical role in the history of cancer research. Discovered in 1911 by Peyton Rous (1) at the Rockefeller Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campaign to focus attention on viruses as etiological agents in cancer, his plat- form having been the chemical characterization of the tobacco mosaic virus as a pure protein-correction, ribonucleoprotein-in 1935 (2). This doctrine was a centerpiece of the U.S. National Cancer Crusade of 1971: if human cancers were caused by viruses, the central task was to isolate them and prepare vaccines for immunization. At that point, many observers felt that perhaps too much attention was being devoted to cancer viruses. It was problematic whether viruses played an etiological role in more than a handful of human cancers.

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