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portada Therapeutic Applications of Quadruplex Nucleic Acids
Type
Physical Book
Publisher
Year
2016
Language
English
Pages
208
Format
Paperback
ISBN13
9780128103722
Edition No.
1
Categories

Therapeutic Applications of Quadruplex Nucleic Acids

Stephen Neidle (Author) · Academic Press · Paperback

Therapeutic Applications of Quadruplex Nucleic Acids - Stephen Neidle

Physical Book

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Synopsis "Therapeutic Applications of Quadruplex Nucleic Acids"

The study of G-quadruplexes has emerged in recent years as an important focus of research in nucleic acids. This is now a rapidly growing area, not least because of its potential as a novel approach to cancer therapeutics, and there is much current activity on the design of quadruplex-selective small-molecule ligands and the study of their cellular effects. This timely publication gives a uniquely integrated view of quadruplex nucleic acids that will be a major resource in future drug-discovery strategies. Therapeutic Applications of Quadruplex Nucleic Acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics. Written by a world leader in this field, this book is a vital resource for researchers in medicinal chemistry, chemical biology, structural biology, drug discovery, and pharmacology in cancer and other therapeutic areas, as well as for chemists and biologists working on nucleic acids, and will be useful for both active researchers and students in these areas.

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