Share
integrins & anti-integrins: links of the chain: autoimmune disease anti-integrins virus disease
Vanadiya Ermekova
(Author)
·
iUniverse
· Paperback
integrins & anti-integrins: links of the chain: autoimmune disease anti-integrins virus disease - Ermekova, Vanadiya
Choose the list to add your product or create one New List
✓ Product added successfully to the Wishlist.
Go to My Wishlists
Origin: U.S.A.
(Import costs included in the price)
It will be shipped from our warehouse between
Friday, July 12 and
Friday, July 19.
You will receive it anywhere in United Kingdom between 1 and 3 business days after shipment.
Synopsis "integrins & anti-integrins: links of the chain: autoimmune disease anti-integrins virus disease"
Integrins play a critical role in numerous vital processes on the systemic, tissue, cell, and molecular levels. These include homeostasis; immunity; hematopoiesis; fertility and embryogenesis; cell proliferation, differentiation, cell cycle division and apoptosis; and gene expression. Impairment of integrins' functions causes the dramatic remodeling of these processes. Prolonged therapy with anti-α4β antibodies may result in severe pathological consequences, including generalized immunosuppression leading to an extreme risk of very serious infections; uncontrolled proliferation and altered differentiation of hematopoietic cells possibly leading to hematological abnormalities and increased risk of malignancies; and alterations in spermatogenesis, fertility, and embryonic development. Natalizumab (Tysabri) is an impressively effective drug. In the professional opinion of well-known neurologists it is considered to be a promising agent for the treatment of multiple sclerosis. However, whereas the evaluation of the drug's benefits can be done by neurologists alone, it is mandatory that the risk in using this agent should be assessed by a team of experts in a number of fields: immunology, infectious diseases, hematology, oncology, and embryology. It is essential to recognize that innovative integrin-antagonist therapy, e.g. therapy with anti-α4β integrin monoclonal antibodies, must be handled with extreme caution.
- 0% (0)
- 0% (0)
- 0% (0)
- 0% (0)
- 0% (0)
All books in our catalog are Original.
The book is written in English.
The binding of this edition is Paperback.
✓ Producto agregado correctamente al carro, Ir a Pagar.
